MLB.com's No. 36 prospect allowed an unearned run on four hits and three walks while striking out seven over six innings before the Chattanooga Lookouts beat the Mississippi Braves, 4-1, in 11 innings.
The 20-year-old right-hander threw 52 of 81 pitches for strikes but did not factor in the decision, exiting a 1-1 tie.
Selected by the Dodgers with the 28th overall pick in the 2010 Draft, Lee induced an around-the-horn double play in the first inning before stranding Christian Bethancourt in scoring position in the second.
Los Angeles' top prospect worked around a pair of two-out baserunners in the third and got help in the fourth from catcher Matt Wallach, who threw out Todd Cunningham trying to steal second.
Lee was not as fortunate in the fifth. Second baseman Rafael Ynoa misplayed Aldren Carrithers' ground ball to open the inning, Greg Paiml singled to right field and Gary Moran advanced both runners with a sacrifice.
Keenan Wiley followed with a line drive to left field to put the Braves on the board, but Lee set down the next two batters to minimize the damage.
In the sixth, Braves' No. 6 prospectJoey Terdoslavich walked on six pitches after falling behind, 0-2, but Cunningham hit into a double play and Bethancourt struck out on Lee's last pitch.
Prior to his promotion, the Texas native was 2-3 with a 4.55 ERA in 12 starts in the hitter-friendly California League. In his rookie season with Class A Great Lakes last year, he was 9-6 with a 3.47 ERA in 24 outings. He struck out 91 batters over 109 innings and held opponents to a .242 average.
Javier Solano (1-0) tossed a hitless 10th to earn his first win of the year and Steve Ames and worked around a hit in the 11th to notch his sixth save.
Ynoa, J.T. Wise and Jake Lemmerman each collected two hits fr the Lookouts, who got a three-run homer from Kyle Russell.